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A quasi-nonlinear analysis of the anisotropic behaviour of human gallbladder wall.
Li, W G; Luo, X Y; Hill, N A; Ogden, R W; Smythe, A; Majeed, A W; Bird, N.
Afiliação
  • Li WG; School of Mathematics and Statistics, University of Glasgow, Glasgow, G12 8QW, UK.
J Biomech Eng ; 134(10): 101009, 2012 Oct.
Article em En | MEDLINE | ID: mdl-23083200
ABSTRACT
Estimation of biomechanical parameters of soft tissues from noninvasive measurements has clinical significance in patient-specific modeling and disease diagnosis. In this work, we present a quasi-nonlinear method that is used to estimate the elastic moduli of the human gallbladder wall. A forward approach based on a transversely isotropic membrane material model is used, and an inverse iteration is carried out to determine the elastic moduli in the circumferential and longitudinal directions between two successive ultrasound images of gallbladder. The results demonstrate that the human gallbladder behaves in an anisotropic manner, and constitutive models need to incorporate this. The estimated moduli are also nonlinear and patient dependent. Importantly, the peak stress predicted here differs from the earlier estimate from linear membrane theory. As the peak stress inside the gallbladder wall has been found to strongly correlate with acalculous gallbladder pain, reliable mechanical modeling for gallbladder tissue is crucial if this information is to be used in clinical diagnosis.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dinâmica não Linear / Técnicas de Imagem por Elasticidade / Módulo de Elasticidade / Vesícula Biliar Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Biomech Eng Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dinâmica não Linear / Técnicas de Imagem por Elasticidade / Módulo de Elasticidade / Vesícula Biliar Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Biomech Eng Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Reino Unido