Clerodane diterpenoids from Croton crassifolius.
J Nat Prod
; 75(12): 2188-92, 2012 Dec 28.
Article
em En
| MEDLINE
| ID: mdl-23194476
ABSTRACT
Seven new clerodane diterpenoids (1-7) were isolated from roots of Croton crassifolius, along with six known compounds. The structures were elucidated by extensive spectroscopic methods (IR, UV, HRESIMS, 1D NMR, and 2D NMR), and the structures of 1, 3, 4, and 7 were confirmed by single-crystal X-ray diffraction analyses. Compounds 1-13 were evaluated for in vitro antiviral activity against herpes simplex virus type 1 using the cytopathic effect reduction assay.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Medicamentos de Ervas Chinesas
/
Croton
/
Citotoxinas
/
Diterpenos Clerodânicos
Limite:
Animals
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2012
Tipo de documento:
Article