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Isoprostanes and neuroprostanes: total synthesis, biological activity and biomarkers of oxidative stress in humans.
Galano, Jean-Marie; Mas, Emilie; Barden, Anne; Mori, Trevor A; Signorini, Cinzia; De Felice, Claudio; Barrett, Aaron; Opere, Catherine; Pinot, Edith; Schwedhelm, Edzard; Benndorf, Ralf; Roy, Jérôme; Le Guennec, Jean-Yves; Oger, Camille; Durand, Thierry.
Afiliação
  • Galano JM; Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 - CNRS - University Montpellier I and II - ENSCM, Faculty of Pharmacy, Montpellier, France.
Prostaglandins Other Lipid Mediat ; 107: 95-102, 2013 Dec.
Article em En | MEDLINE | ID: mdl-23644158
Isoprostanes (IsoPs) and neuroprostanes (NeuroPs) are formed in vivo by a free radical non-enzymatic mechanism involving peroxidation of arachidonic acid (AA, C20:4 n-6) and docosahexaenoic acid (DHA, C22:6 n-3) respectively. This review summarises our research in the total synthesis of these lipid metabolites, as well as their biological activities and their utility as biomarkers of oxidative stress in humans.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Isoprostanos / Neuroprostanos Limite: Animals / Humans Idioma: En Revista: Prostaglandins Other Lipid Mediat Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Isoprostanos / Neuroprostanos Limite: Animals / Humans Idioma: En Revista: Prostaglandins Other Lipid Mediat Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: França