Dosage compensation of an aneuploid genome in mouse spermatogenic cells.

Jansa, Petr; Homolka, David; Blatny, Radek; Mistrik, Martin; Bartek, Jiri; Forejt, Jiri

Jansa, Petr; Homolka, David; Blatny, Radek; Mistrik, Martin; Bartek, Jiri; Forejt, Jiri.

Afiliação

Jansa P; Laboratory of Mouse Molecular Genetics Division BIOCEV, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Homolka D; Laboratory of Mouse Molecular Genetics Division BIOCEV, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Blatny R; Laboratory of Mouse Molecular Genetics Division BIOCEV, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Mistrik M; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Czech Republic.
Bartek J; Laboratory of Genome Integrity, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Czech Republic Danish Cancer Society Research Center, C
Forejt J; Laboratory of Mouse Molecular Genetics Division BIOCEV, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic jforejt@img.cas.cz.

Biol Reprod ; 90(6): 124, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24790161

Assuntos

Mecanismo Genético de Compensação de Dose; Genoma; Infertilidade Masculina/genética; Meiose/genética; Espermatócitos/fisiologia; Trissomia/genética; Aneuploidia; Animais; Peso Corporal/genética; Cromatina/genética; Feminino; Fígado/fisiologia; Masculino; Camundongos Endogâmicos C57BL; Fenótipo; Gravidez; Complexo Sinaptonêmico/genética; Transcriptoma; Translocação Genética/genética

Palavras-chave

gene dosage; male sterility; meiotic silencing of unsynapsed chromatin; pachytene spermatocytes; segmental trisomy; synaptonemal complex; transcriptional profiling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espermatócitos / Trissomia / Mecanismo Genético de Compensação de Dose / Genoma / Infertilidade Masculina / Meiose Limite: Animals / Pregnancy Idioma: En Revista: Biol Reprod Ano de publicação: 2014 Tipo de documento: Article País de afiliação: República Tcheca

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