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Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality.
Xu, Hua; Aldrich, Melinda C; Chen, Qingxia; Liu, Hongfang; Peterson, Neeraja B; Dai, Qi; Levy, Mia; Shah, Anushi; Han, Xue; Ruan, Xiaoyang; Jiang, Min; Li, Ying; Julien, Jamii St; Warner, Jeremy; Friedman, Carol; Roden, Dan M; Denny, Joshua C.
Afiliação
  • Xu H; The University of Texas School of Biomedical Informatics at Houston, Houston, Texas, USA.
  • Aldrich MC; Department of Thoracic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Chen Q; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Liu H; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
  • Peterson NB; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Dai Q; Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Levy M; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Shah A; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Han X; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Ruan X; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
  • Jiang M; The University of Texas School of Biomedical Informatics at Houston, Houston, Texas, USA.
  • Li Y; Department of Biomedical Informatics, Columbia University, New York, New York, USA.
  • Julien JS; Department of Thoracic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Warner J; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Friedman C; Department of Biomedical Informatics, Columbia University, New York, New York, USA.
  • Roden DM; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Denny JC; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
J Am Med Inform Assoc ; 22(1): 179-91, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25053577
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Armazenamento e Recuperação da Informação / Registros Eletrônicos de Saúde / Reposicionamento de Medicamentos / Hipoglicemiantes / Metformina / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Revista: J Am Med Inform Assoc Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Armazenamento e Recuperação da Informação / Registros Eletrônicos de Saúde / Reposicionamento de Medicamentos / Hipoglicemiantes / Metformina / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Revista: J Am Med Inform Assoc Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos