Quantitative determination of decitabine incorporation into DNA and its effect on mutation rates in human cancer cells.

Öz, Simin; Raddatz, Günter; Rius, Maria; Blagitko-Dorfs, Nadja; Lübbert, Michael; Maercker, Christian; Lyko, Frank

Öz, Simin; Raddatz, Günter; Rius, Maria; Blagitko-Dorfs, Nadja; Lübbert, Michael; Maercker, Christian; Lyko, Frank.

Afiliação

Öz S; Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 69120 Heidelberg, Germany.
Raddatz G; Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 69120 Heidelberg, Germany.
Rius M; Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 69120 Heidelberg, Germany.
Blagitko-Dorfs N; Department of Hematology, University of Freiburg Medical Center, 79106 Freiburg, Germany.
Lübbert M; Department of Hematology, University of Freiburg Medical Center, 79106 Freiburg, Germany.
Maercker C; Esslingen University of Applied Sciences, 73728 Esslingen, Germany Genomics and Proteomics Core Facility, German Cancer Research Center, 69120 Heidelberg, Germany.
Lyko F; Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 69120 Heidelberg, Germany f.lyko@dkfz.de.

Nucleic Acids Res ; 42(19): e152, 2014 Oct 29.

Article em En | MEDLINE | ID: mdl-25159616

Assuntos

Antimetabólitos Antineoplásicos/análise; Azacitidina/análogos & derivados; DNA de Neoplasias/química; Taxa de Mutação; Azacitidina/análise; Linhagem Celular Tumoral; Decitabina; Humanos; Contagem de Cintilação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / DNA de Neoplasias / Taxa de Mutação / Antimetabólitos Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha

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