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Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage.
Rasmussen, Mikkel A; Holst, Bjørn; Tümer, Zeynep; Johnsen, Mads G; Zhou, Shuling; Stummann, Tina C; Hyttel, Poul; Clausen, Christian.
Afiliação
  • Rasmussen MA; Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Groennegaardsvej 7, Frederiksberg C 1870, Denmark. Electronic address: mar@bioneer.dk.
  • Holst B; Bioneer A/S, Kogle Alle 2, Hoersholm 2970, Denmark.
  • Tümer Z; Applied Human Molecular Genetics, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, Gl. Landevej 7, Glostrup 2600, Denmark.
  • Johnsen MG; Bioneer A/S, Kogle Alle 2, Hoersholm 2970, Denmark.
  • Zhou S; Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Groennegaardsvej 7, Frederiksberg C 1870, Denmark.
  • Stummann TC; H. Lundbeck A/S, Ottiliavej 9, Valby 2500, Denmark.
  • Hyttel P; Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Groennegaardsvej 7, Frederiksberg C 1870, Denmark.
  • Clausen C; Bioneer A/S, Kogle Alle 2, Hoersholm 2970, Denmark.
Stem Cell Reports ; 3(3): 404-13, 2014 Sep 09.
Article em En | MEDLINE | ID: mdl-25241739

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Proteína Supressora de Tumor p53 / Apoptose / Reprogramação Celular / Células-Tronco Pluripotentes Induzidas / Fibroblastos Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Proteína Supressora de Tumor p53 / Apoptose / Reprogramação Celular / Células-Tronco Pluripotentes Induzidas / Fibroblastos Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2014 Tipo de documento: Article