Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults.

Mohanty, Subhasis; Joshi, Samit R; Ueda, Ikuyo; Wilson, Jean; Blevins, Tamara P; Siconolfi, Barbara; Meng, Hailong; Devine, Lesley; Raddassi, Khadir; Tsang, Sui; Belshe, Robert B; Hafler, David A; Kaech, Susan M; Kleinstein, Steven H; Trentalange, Mark; Allore, Heather G; Shaw, Albert C

Mohanty, Subhasis; Joshi, Samit R; Ueda, Ikuyo; Wilson, Jean; Blevins, Tamara P; Siconolfi, Barbara; Meng, Hailong; Devine, Lesley; Raddassi, Khadir; Tsang, Sui; Belshe, Robert B; Hafler, David A; Kaech, Susan M; Kleinstein, Steven H; Trentalange, Mark; Allore, Heather G; Shaw, Albert C.

Afiliação

Mohanty S; Section of Infectious Diseases, Department of Internal Medicine.
Joshi SR; Section of Infectious Diseases, Department of Internal Medicine.
Ueda I; Section of Infectious Diseases, Department of Internal Medicine.
Wilson J; Section of Infectious Diseases, Department of Internal Medicine.
Blevins TP; Department of Center for Vaccine Development, Saint Louis University, Missouri.
Siconolfi B; Section of Infectious Diseases, Department of Internal Medicine.
Meng H; Department of Pathology.
Devine L; Department of Laboratory Medicine.
Raddassi K; Department of Neurology.
Tsang S; Section of Infectious Diseases, Department of Internal Medicine.
Belshe RB; Department of Center for Vaccine Development, Saint Louis University, Missouri.
Hafler DA; Department of Neurology Department of Immunobiology.
Kaech SM; Department of Immunobiology.
Kleinstein SH; Department of Pathology Department of Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut.
Trentalange M; Department of Internal Medicine, Yale School of Medicine.
Allore HG; Department of Internal Medicine, Yale School of Medicine.
Shaw AC; Section of Infectious Diseases, Department of Internal Medicine.

J Infect Dis ; 211(7): 1174-84, 2015 Apr 01.

Article em En | MEDLINE | ID: mdl-25367297

Assuntos

Citocinas/metabolismo; Vacinas contra Influenza/imunologia; Influenza Humana/prevenção & controle; Interleucina-10/metabolismo; Monócitos/metabolismo; Adulto; Fatores Etários; Idoso; Citocinas/imunologia; Fosfatase 1 de Especificidade Dupla/imunologia; Fosfatase 1 de Especificidade Dupla/metabolismo; Feminino; Proteínas Ligadas por GPI/imunologia; Proteínas Ligadas por GPI/metabolismo; Regulação da Expressão Gênica/imunologia; Humanos; Imunidade Inata; Influenza Humana/imunologia; Influenza Humana/virologia; Interleucina-10/imunologia; Interleucina-6/imunologia; Interleucina-6/metabolismo; Receptores de Lipopolissacarídeos/imunologia; Receptores de Lipopolissacarídeos/metabolismo; Masculino; Monócitos/imunologia; Fosforilação; Receptores de IgG/imunologia; Receptores de IgG/metabolismo; Fator de Transcrição STAT3/imunologia; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais/imunologia; Fator de Necrose Tumoral alfa/imunologia; Fator de Necrose Tumoral alfa/metabolismo; Vacinação; Adulto Jovem

Palavras-chave

aging; cytokine; influenza vaccine; innate immunity; monocyte

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Monócitos / Citocinas / Interleucina-10 / Influenza Humana Idioma: En Revista: J Infect Dis Ano de publicação: 2015 Tipo de documento: Article

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