Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor.

Ju, Hye-Lim; Calvisi, Diego F; Moon, Hyuk; Baek, Sinhwa; Ribback, Silvia; Dombrowski, Frank; Cho, Kyung Joo; Chung, Sook In; Han, Kwang-Hyub; Ro, Simon Weonsang

Ju, Hye-Lim; Calvisi, Diego F; Moon, Hyuk; Baek, Sinhwa; Ribback, Silvia; Dombrowski, Frank; Cho, Kyung Joo; Chung, Sook In; Han, Kwang-Hyub; Ro, Simon Weonsang.

Afiliação

Ju HL; 1] Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea [2] Brain Korea 21 Project for Medical Science College of Medicine, Yonsei University, Seoul, Korea.
Calvisi DF; Institute of Pathology, University Medicine Greifswald, Greifswald, Germany.
Moon H; 1] Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea [2] Brain Korea 21 Project for Medical Science College of Medicine, Yonsei University, Seoul, Korea.
Baek S; 1] Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea [2] Brain Korea 21 Project for Medical Science College of Medicine, Yonsei University, Seoul, Korea.
Ribback S; Institute of Pathology, University Medicine Greifswald, Greifswald, Germany.
Dombrowski F; Institute of Pathology, University Medicine Greifswald, Greifswald, Germany.
Cho KJ; Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea.
Chung SI; 1] Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea [2] Brain Korea 21 Project for Medical Science College of Medicine, Yonsei University, Seoul, Korea.
Han KH; 1] Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea [2] Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Ro SW; 1] Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul, Korea [2] Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Sci Rep ; 5: 8053, 2015 Jan 27.

Article em En | MEDLINE | ID: mdl-25623590

Assuntos

Proteínas de Fluorescência Verde/metabolismo; Neoplasias Hepáticas/patologia; Luciferases/metabolismo; Proteínas Proto-Oncogênicas p21(ras)/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Animais; Proliferação de Células; Modelos Animais de Doenças; Genes Reporter; Proteínas de Fluorescência Verde/genética; Fígado/metabolismo; Fígado/patologia; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/mortalidade; Luciferases/genética; Medições Luminescentes; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Células NIH 3T3; Fases de Leitura Aberta/genética; Imagem Óptica; Proteínas Proto-Oncogênicas p21(ras)/genética; Reação em Cadeia da Polimerase em Tempo Real; Pele/metabolismo; Pele/patologia; Taxa de Sobrevida; Proteína Supressora de Tumor p53/genética

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas p21(ras) / Proteínas de Fluorescência Verde / Neoplasias Hepáticas / Luciferases Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google