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3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae.
Verma, Astha; Wong, Dawn M; Islam, Rafique; Tong, Fan; Ghavami, Maryam; Mutunga, James M; Slebodnick, Carla; Li, Jianyong; Viayna, Elisabet; Lam, Polo C-H; Totrov, Maxim M; Bloomquist, Jeffrey R; Carlier, Paul R.
Afiliação
  • Verma A; Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA.
  • Wong DM; Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA.
  • Islam R; Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
  • Tong F; Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
  • Ghavami M; Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA.
  • Mutunga JM; Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
  • Slebodnick C; Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA.
  • Li J; Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.
  • Viayna E; Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA.
  • Lam PC; Molsoft LLC, 11199 Sorrento Valley Road, San Diego, CA 92121, USA.
  • Totrov MM; Molsoft LLC, 11199 Sorrento Valley Road, San Diego, CA 92121, USA.
  • Bloomquist JR; Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
  • Carlier PR; Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address: pcarlier@vt.edu.
Bioorg Med Chem ; 23(6): 1321-40, 2015 Mar 15.
Article em En | MEDLINE | ID: mdl-25684426
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolinesterase / Carbamatos / Inibidores da Colinesterase / Isoxazóis / Malária / Anopheles Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolinesterase / Carbamatos / Inibidores da Colinesterase / Isoxazóis / Malária / Anopheles Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos