Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.

Dahms, Sven O; Mayer, Magnus C; Roeser, Dirk; Multhaup, Gerd; Than, Manuel E

Dahms, Sven O; Mayer, Magnus C; Roeser, Dirk; Multhaup, Gerd; Than, Manuel E.

Afiliação

Dahms SO; Protein Crystallography Group, Leibniz Institute for Age Research (FLI), Beutenbergstrasse 11, 07745 Jena, Germany.
Mayer MC; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany.
Roeser D; Protein Crystallography Group, Leibniz Institute for Age Research (FLI), Beutenbergstrasse 11, 07745 Jena, Germany.
Multhaup G; Department of Pharmacology and Therapeutics, McGill University Montreal, Montreal, Quebec H3G 1Y6, Canada.
Than ME; Protein Crystallography Group, Leibniz Institute for Age Research (FLI), Beutenbergstrasse 11, 07745 Jena, Germany.

Acta Crystallogr D Biol Crystallogr ; 71(Pt 3): 494-504, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25760599

Assuntos

Precursor de Proteína beta-Amiloide/química; Heparina/química; Humanos; Estrutura Secundária de Proteína; Estrutura Terciária de Proteína

Palavras-chave

APP-like protein 1; Alzheimer's disease; heparan sulfate binding domain; protein heparin complex

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heparina / Precursor de Proteína beta-Amiloide Limite: Humans Idioma: En Revista: Acta Crystallogr D Biol Crystallogr Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google