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Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.
Tokarski, John S; Zupa-Fernandez, Adriana; Tredup, Jeffrey A; Pike, Kristen; Chang, ChiehYing; Xie, Dianlin; Cheng, Lihong; Pedicord, Donna; Muckelbauer, Jodi; Johnson, Stephen R; Wu, Sophie; Edavettal, Suzanne C; Hong, Yang; Witmer, Mark R; Elkin, Lisa L; Blat, Yuval; Pitts, William J; Weinstein, David S; Burke, James R.
Afiliação
  • Tokarski JS; From the Departments of Molecular Structure and Design.
  • Zupa-Fernandez A; Immunosciences Biology.
  • Tredup JA; Protein Science.
  • Pike K; the Department of Leads Discovery and Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut 06492.
  • Chang C; From the Departments of Molecular Structure and Design.
  • Xie D; Protein Science.
  • Cheng L; Immunosciences Biology.
  • Pedicord D; Leads Discovery and Optimization, and.
  • Muckelbauer J; From the Departments of Molecular Structure and Design.
  • Johnson SR; From the Departments of Molecular Structure and Design.
  • Wu S; Protein Science.
  • Edavettal SC; Protein Science.
  • Hong Y; Discovery Chemistry, Bristol-Myers Squibb Research and Development, Princeton, New Jersey 08543 and.
  • Witmer MR; Protein Science.
  • Elkin LL; the Department of Leads Discovery and Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut 06492.
  • Blat Y; Leads Discovery and Optimization, and.
  • Pitts WJ; Discovery Chemistry, Bristol-Myers Squibb Research and Development, Princeton, New Jersey 08543 and.
  • Weinstein DS; Discovery Chemistry, Bristol-Myers Squibb Research and Development, Princeton, New Jersey 08543 and.
  • Burke JR; Immunosciences Biology, james.burke@bms.com.
J Biol Chem ; 290(17): 11061-74, 2015 Apr 24.
Article em En | MEDLINE | ID: mdl-25762719
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Transdução de Sinais / Modelos Moleculares / TYK2 Quinase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Transdução de Sinais / Modelos Moleculares / TYK2 Quinase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article