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Oxypurinol-Specific T Cells Possess Preferential TCR Clonotypes and Express Granulysin in Allopurinol-Induced Severe Cutaneous Adverse Reactions.
Chung, Wen-Hung; Pan, Ren-You; Chu, Mu-Tzu; Chin, See-Wen; Huang, Yu-Lin; Wang, Wei-Chi; Chang, Jen-Yun; Hung, Shuen-Iu.
Afiliação
  • Chung WH; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei and Keelung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Pan RY; Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan.
  • Chu MT; Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.
  • Chin SW; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei and Keelung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Huang YL; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei and Keelung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Wang WC; Health GeneTech Corporation, Taoyuan, Taiwan.
  • Chang JY; Health GeneTech Corporation, Taoyuan, Taiwan.
  • Hung SI; Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan; Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan. Electronic address: sihung@ym.edu.tw.
J Invest Dermatol ; 135(9): 2237-2248, 2015 Sep.
Article em En | MEDLINE | ID: mdl-25946710
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxipurinol / Leucócitos Mononucleares / Ativação Linfocitária / Antígenos de Diferenciação de Linfócitos T / Alopurinol Tipo de estudo: Etiology_studies / Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Invest Dermatol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxipurinol / Leucócitos Mononucleares / Ativação Linfocitária / Antígenos de Diferenciação de Linfócitos T / Alopurinol Tipo de estudo: Etiology_studies / Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Invest Dermatol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Taiwan