Effects of Hemodialysis on Methadone Pharmacokinetics and QTc.

Opdal, Mimi Stokke; Arnesen, Margrete; Müller, Lill Dannevig; Hullstein, Ingunn; Sayed, Karim; Brørs, Odd; Kringen, Marianne; Sagedal, Solbjørg; Gjesdal, Knut; Krajci, Peter

Opdal, Mimi Stokke; Arnesen, Margrete; Müller, Lill Dannevig; Hullstein, Ingunn; Sayed, Karim; Brørs, Odd; Kringen, Marianne; Sagedal, Solbjørg; Gjesdal, Knut; Krajci, Peter.

Afiliação

Opdal MS; Institute of Clinical Medicine, Oslo University, Oslo, Norway; Department of Pharmacology, Oslo University Hospital, Oslo, Norway. Electronic address: uxmist@ous-hf.no.
Arnesen M; Department of Substance Use Disorder Treatment, Oslo University Hospital, Oslo, Norway.
Müller LD; Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
Hullstein I; Department of Pharmacology, Oslo University Hospital, Oslo, Norway; Norwegian Doping Control Laboratory, Oslo University Hospital, Oslo, Norway.
Sayed K; Salvation Army Hospital, Oslo, Norway.
Brørs O; Institute of Clinical Medicine, Oslo University, Oslo, Norway.
Kringen M; Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
Sagedal S; Department of Nephrology, Oslo University Hospital, Oslo, Norway.
Gjesdal K; Institute of Clinical Medicine, Oslo University, Oslo, Norway; Department of Cardiology, Oslo University Hospital, Oslo, Norway.
Krajci P; Department of Substance Use Disorder Treatment, Oslo University Hospital, Oslo, Norway.

Clin Ther ; 37(7): 1594-9, 2015 Jul 01.

Article em En | MEDLINE | ID: mdl-25963997

Assuntos

Metadona/farmacocinética; Tratamento de Substituição de Opiáceos/métodos; Diálise Renal/métodos; Idoso; Eletrocardiografia; Feminino; Soluções para Hemodiálise/química; Humanos; Falência Renal Crônica/metabolismo; Falência Renal Crônica/terapia; Síndrome do QT Longo/etiologia; Masculino; Diálise Renal/efeitos adversos; Espectrometria de Massas em Tandem/métodos

Palavras-chave

QTc; hemodialysis; methadone; methadone maintenance treatment; pharmacokinetics; renal failure

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diálise Renal / Tratamento de Substituição de Opiáceos / Metadona Tipo de estudo: Etiology_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Clin Ther Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google