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Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.
Lee, Hyunbeom; Le, Hoang V; Wu, Rui; Doud, Emma; Sanishvili, Ruslan; Kellie, John F; Compton, Phillip D; Pachaiyappan, Boobalan; Liu, Dali; Kelleher, Neil L; Silverman, Richard B.
Afiliação
  • Lee H; Departments of Chemistry and Molecular Biosciences, Chemistry of Life Processes Institute, and the Center for Molecular Innovation and Drug Discovery, Northwestern University , Evanston, Illinois 60208, United States.
  • Le HV; Departments of Chemistry and Molecular Biosciences, Chemistry of Life Processes Institute, and the Center for Molecular Innovation and Drug Discovery, Northwestern University , Evanston, Illinois 60208, United States.
  • Wu R; Department of Chemistry and Biochemistry, Loyola University Chicago , Chicago, Illinois 60660, United States.
  • Doud E; Departments of Chemistry and Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University , Evanston, Illinois 60208, United States.
  • Sanishvili R; X-ray Science Division, Advanced Photon Source, Argonne National Laboratory , Lemont, Illinois 60439, United States.
  • Kellie JF; Departments of Chemistry and Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University , Evanston, Illinois 60208, United States.
  • Compton PD; Departments of Chemistry and Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University , Evanston, Illinois 60208, United States.
  • Pachaiyappan B; Departments of Chemistry and Molecular Biosciences, Chemistry of Life Processes Institute, and the Center for Molecular Innovation and Drug Discovery, Northwestern University , Evanston, Illinois 60208, United States.
  • Liu D; Department of Chemistry and Biochemistry, Loyola University Chicago , Chicago, Illinois 60660, United States.
  • Kelleher NL; Departments of Chemistry and Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University , Evanston, Illinois 60208, United States.
  • Silverman RB; Departments of Chemistry and Molecular Biosciences, Chemistry of Life Processes Institute, and the Center for Molecular Innovation and Drug Discovery, Northwestern University , Evanston, Illinois 60208, United States.
ACS Chem Biol ; 10(9): 2087-98, 2015 Sep 18.
Article em En | MEDLINE | ID: mdl-26110556

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prolina / Inibidores Enzimáticos / 4-Aminobutirato Transaminase Limite: Animals Idioma: En Revista: ACS Chem Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prolina / Inibidores Enzimáticos / 4-Aminobutirato Transaminase Limite: Animals Idioma: En Revista: ACS Chem Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos