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A Prolonged Post-Operative Antibiotic Regimen Reduced the Rate of Prosthetic Joint Infection after Aseptic Revision Knee Arthroplasty.
Claret, Guillem; Tornero, Eduard; Martínez-Pastor, Juan-Carlos; Piazuelo, Mercè; Martínez, Jésica; Bosch, Jordi; Mensa, Josep; Soriano, Alex.
Afiliação
  • Claret G; 1 Departments of Orthopedic Surgery, Hospital Clínic of Barcelona , Spain, Barcelona, Spain .
  • Tornero E; 1 Departments of Orthopedic Surgery, Hospital Clínic of Barcelona , Spain, Barcelona, Spain .
  • Martínez-Pastor JC; 1 Departments of Orthopedic Surgery, Hospital Clínic of Barcelona , Spain, Barcelona, Spain .
  • Piazuelo M; 1 Departments of Orthopedic Surgery, Hospital Clínic of Barcelona , Spain, Barcelona, Spain .
  • Martínez J; 1 Departments of Orthopedic Surgery, Hospital Clínic of Barcelona , Spain, Barcelona, Spain .
  • Bosch J; 2 Service of Infectious Diseases, Hospital Clínic of Barcelona, Spain, IDIBAPS, University of Barcelona , Barcelona, Spain .
  • Mensa J; 2 Service of Infectious Diseases, Hospital Clínic of Barcelona, Spain, IDIBAPS, University of Barcelona , Barcelona, Spain .
  • Soriano A; 2 Service of Infectious Diseases, Hospital Clínic of Barcelona, Spain, IDIBAPS, University of Barcelona , Barcelona, Spain .
Surg Infect (Larchmt) ; 16(6): 775-80, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26241469
BACKGROUND: The aim of this study was to compare the prosthetic joint infection (PJI) rate after knee revision arthroplasty in two consecutive periods with different antibiotic prophylaxis: short (one day) versus long (five days). METHODS: From January 2007 to September 2010 antibiotic prophylaxis consisted of 800 mg of teicoplanin and 2 g of ceftazidime intravenously and 1 g of ceftazidime two hours after the first dose. From October 2010, it was prolonged post-operatively using vancomycin and ceftazidime intravenously until the fifth day. RESULTS: During the study period, 341 revision surgeries met the inclusion criteria. The PJI rate was lower in the long-prophylaxis group (2.2% versus 6.9%, p=0.049). Prolonged post-operative antibiotic treatment was the only variable associated independently with a lower rate of PJI (odds ratio [OR]: 0.27, 95% confidence interval [CI]: 0.07-0.99).
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cuidados Pós-Operatórios / Artrite / Infecções Relacionadas à Prótese / Antibioticoprofilaxia / Artroplastia do Joelho / Antibacterianos Tipo de estudo: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Surg Infect (Larchmt) Assunto da revista: BACTERIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cuidados Pós-Operatórios / Artrite / Infecções Relacionadas à Prótese / Antibioticoprofilaxia / Artroplastia do Joelho / Antibacterianos Tipo de estudo: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Surg Infect (Larchmt) Assunto da revista: BACTERIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Espanha