Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons.

Brettle, Merryn; Suchowerska, Alexandra K; Chua, Sook W; Ittner, Lars M; Fath, Thomas

Brettle, Merryn; Suchowerska, Alexandra K; Chua, Sook W; Ittner, Lars M; Fath, Thomas.

Afiliação

Brettle M; Neurodegeneration and Repair Unit, School of Medical Sciences, University of New South Wales, Australia.
Suchowerska AK; Neurodegeneration and Repair Unit, School of Medical Sciences, University of New South Wales, Australia.
Chua SW; Dementia Research Unit, School of Medical Sciences, University of New South Wales, Australia.
Ittner LM; Dementia Research Unit, School of Medical Sciences, University of New South Wales, Australia. Electronic address: l.ittner@unsw.edu.au.
Fath T; Neurodegeneration and Repair Unit, School of Medical Sciences, University of New South Wales, Australia. Electronic address: t.fath@unsw.edu.au.

Neurosci Lett ; 609: 223-8, 2015 Nov 16.

Article em En | MEDLINE | ID: mdl-26499959

Assuntos

Esclerose Lateral Amiotrófica/genética; Dendritos/ultraestrutura; Hipocampo/citologia; Profilinas/metabolismo; Animais; Dendritos/metabolismo; Espinhas Dendríticas/metabolismo; Espinhas Dendríticas/ultraestrutura; Células HEK293; Humanos; Camundongos Endogâmicos C57BL; Mutação; Neurônios/metabolismo; Neurônios/ultraestrutura; Cultura Primária de Células; Profilinas/genética; Agregados Proteicos

Palavras-chave

Actin cytoskeleton; Amyotrophic lateral sclerosis; Profilin 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dendritos / Profilinas / Hipocampo / Esclerose Lateral Amiotrófica Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Neurosci Lett Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália

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