Triage biodosimetry using centromeric/telomeric PNA probes and Giemsa staining to score dicentrics or excess fragments in non-stimulated lymphocyte prematurely condensed chromosomes.

Karachristou, Ioanna; Karakosta, Maria; Pantelias, Antonio; Hatzi, Vasiliki I; Karaiskos, Pantelis; Dimitriou, Panagiotis; Pantelias, Gabriel; Terzoudi, Georgia I

Karachristou, Ioanna; Karakosta, Maria; Pantelias, Antonio; Hatzi, Vasiliki I; Karaiskos, Pantelis; Dimitriou, Panagiotis; Pantelias, Gabriel; Terzoudi, Georgia I.

Afiliação

Karachristou I; Laboratory of Health Physics, Radiobiology & Cytogenetics, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", Athens, Greece.
Karakosta M; Laboratory of Health Physics, Radiobiology & Cytogenetics, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", Athens, Greece.
Pantelias A; Laboratory of Health Physics, Radiobiology & Cytogenetics, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", Athens, Greece.
Hatzi VI; Laboratory of Health Physics, Radiobiology & Cytogenetics, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", Athens, Greece.
Karaiskos P; Medical Physics Laboratory, Medical School, University of Athens, Greece.
Dimitriou P; Medical Physics Laboratory, Medical School, University of Athens, Greece.
Pantelias G; Laboratory of Health Physics, Radiobiology & Cytogenetics, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", Athens, Greece.
Terzoudi GI; Laboratory of Health Physics, Radiobiology & Cytogenetics, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", Athens, Greece. Electronic address: gterzoudi@rrp.demokritos.gr.

Mutat Res Genet Toxicol Environ Mutagen ; 793: 107-14, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26520380

Assuntos

Centrômero/genética; Aberrações Cromossômicas; Linfócitos/efeitos da radiação; Ácidos Nucleicos Peptídicos/genética; Radiometria/métodos; Corantes Azur; Células Cultivadas; Sondas de DNA/genética; Humanos; Hibridização in Situ Fluorescente; Linfócitos/citologia; Fase de Repouso do Ciclo Celular; Telômero/genética; Triagem/métodos

Palavras-chave

Cell fusion; Centromere/telomere staining; Excess PCC fragments; PNA-FISH; Premature chromosome condensation; Triage biodosimetry

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radiometria / Linfócitos / Centrômero / Aberrações Cromossômicas / Ácidos Nucleicos Peptídicos Limite: Humans Idioma: En Revista: Mutat Res Genet Toxicol Environ Mutagen Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Grécia

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