Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit.
Clin Ophthalmol
; 9: 1965-71, 2015.
Article
em En
| MEDLINE
| ID: mdl-26543348
ABSTRACT
PURPOSE:
To evaluate the anatomical and functional results obtained with pars plana vitrectomy (PPV) plus autologous platelet concentrate (APC) as a treatment for macular detachment associated with optic disc pit (ODP).METHODS:
We performed a prospective interventional study of 19 eyes of 19 consecutive patients with posterior macular detachment due to ODP. All patients underwent PPV, posterior hyaloid peeling, fluid-air exchange, injection of 0.05 mL of APC over the ODP and 15% perfluoropropane (C3F8) endotamponade. Postoperative measures included face-up positioning for 2 hours and then avoidance of the face-up position during the ensuing 10 days. All patients underwent complete ophthalmologic examination and optical coherence tomography preoperatively at 1 month, 3 months, 6 months, 9 months, and 12 months postoperatively and then annually. Outcome measures were best corrected visual acuity (BCVA) by logMAR, improvement of quality of vision, macular attachment, and resolution of intraretinal schisis-like separation.RESULTS:
Preoperatively, the median BCVA was 0.70 (range 0.30-1.70) and all patients showed improved visual acuity after surgery; BCVA was 0.22 (range 0.07-0.52) at 12 months follow-up. All patients showed complete reabsorption of intraretinal fluid (median time 3.5 months [range 2-8 months]) and macular attachment at the end of follow-up (median 60 months [range 12-144 months]), with stable or improved visual acuity. No reoperations were needed and no major adverse events were recorded.CONCLUSION:
For macular detachment associated with ODP, the combination of PPV, posterior hyaloid peeling, APC, and C3F8 tamponade is a highly effective alternative technique with stable anatomical and functional results.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Clin Ophthalmol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Espanha