The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.

Tosh, Kevin W; Mittereder, Lara; Bonne-Annee, Sandra; Hieny, Sara; Nutman, Thomas B; Singer, Steven M; Sher, Alan; Jankovic, Dragana

Tosh, Kevin W; Mittereder, Lara; Bonne-Annee, Sandra; Hieny, Sara; Nutman, Thomas B; Singer, Steven M; Sher, Alan; Jankovic, Dragana.

Afiliação

Tosh KW; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; Department of Biology, Georgetown University, Washington, DC 20057; and.
Mittereder L; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
Bonne-Annee S; Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Hieny S; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
Nutman TB; Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Singer SM; Department of Biology, Georgetown University, Washington, DC 20057; and.
Sher A; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
Jankovic D; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; djankovic@niaid.nih.gov.

J Immunol ; 196(1): 345-56, 2016 Jan 01.

Article em En | MEDLINE | ID: mdl-26597011

Assuntos

Células Dendríticas/imunologia; Interleucina-12/imunologia; Monócitos/imunologia; Toxoplasma/imunologia; Toxoplasmose/imunologia; Antígenos CD1/metabolismo; Células Cultivadas; Feminino; Proteínas Ligadas por GPI/metabolismo; Glicoproteínas/metabolismo; Humanos; Masculino; Fagocitose/imunologia; Receptores de IgG/metabolismo; Transdução de Sinais/imunologia; Toxoplasmose/parasitologia; Fator de Necrose Tumoral alfa/imunologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxoplasma / Células Dendríticas / Monócitos / Toxoplasmose / Interleucina-12 Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: J Immunol Ano de publicação: 2016 Tipo de documento: Article

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