Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma.

Perez-Neut, Mathew; Haar, Lauren; Rao, Vidhya; Santha, Sreevidya; Lansu, Katherine; Rana, Basabi; Jones, Walter K; Gentile, Saverio

Perez-Neut, Mathew; Haar, Lauren; Rao, Vidhya; Santha, Sreevidya; Lansu, Katherine; Rana, Basabi; Jones, Walter K; Gentile, Saverio.

Afiliação

Perez-Neut M; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Haar L; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Rao V; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Santha S; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Lansu K; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Rana B; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Jones WK; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.
Gentile S; Department of Molecular Pharmacology & Therapeutics, Loyola University, Chicago, IL-60153, USA.

Oncotarget ; 7(16): 21991-2004, 2016 Apr 19.

Article em En | MEDLINE | ID: mdl-26942884

Assuntos

Autofagia/fisiologia; Senescência Celular/fisiologia; Canais de Potássio Éter-A-Go-Go/metabolismo; Melanoma/patologia; Linhagem Celular Tumoral; Humanos; Melanoma/metabolismo

Palavras-chave

autophagy; hERG; melanoma; potassium channels; senescence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Senescência Celular / Canais de Potássio Éter-A-Go-Go / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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