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The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.
Gdynia, Georg; Sauer, Sven W; Kopitz, Jürgen; Fuchs, Dominik; Duglova, Katarina; Ruppert, Thorsten; Miller, Matthias; Pahl, Jens; Cerwenka, Adelheid; Enders, Markus; Mairbäurl, Heimo; Kaminski, Marcin M; Penzel, Roland; Zhang, Christine; Fuller, Jonathan C; Wade, Rebecca C; Benner, Axel; Chang-Claude, Jenny; Brenner, Hermann; Hoffmeister, Michael; Zentgraf, Hanswalter; Schirmacher, Peter; Roth, Wilfried.
Afiliação
  • Gdynia G; Institute of Pathology, Department of Surgical Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Sauer SW; German Cancer Research Center, Clinical Cooperation Unit Molecular Tumor Pathology, 69120 Heidelberg, Germany.
  • Kopitz J; Division of Inborn Metabolic Diseases, Department of General Pediatrics, University Children's Hospital, 69120 Heidelberg, Germany.
  • Fuchs D; Institute of Pathology, Department of Surgical Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Duglova K; Institute of Pathology, Department of Surgical Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Ruppert T; Institute of Pathology, Department of Surgical Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Miller M; Division of Inborn Metabolic Diseases, Department of General Pediatrics, University Children's Hospital, 69120 Heidelberg, Germany.
  • Pahl J; German Cancer Research Center, Boveri Junior Research Group Innate Immunity, 69120 Heidelberg, Germany.
  • Cerwenka A; German Cancer Research Center, Boveri Junior Research Group Innate Immunity, 69120 Heidelberg, Germany.
  • Enders M; German Cancer Research Center, Boveri Junior Research Group Innate Immunity, 69120 Heidelberg, Germany.
  • Mairbäurl H; Institute of Inorganic Chemistry, Research Group Enders, University of Heidelberg, 69120 Heidelberg, Germany.
  • Kaminski MM; Medical Clinic VII, Department of Sports Medicine, University of Heidelberg, and Translational Lung Research Center (TLRC), member of the German Center for Lung Research (DZL), 69120 Heidelberg, Germany.
  • Penzel R; German Cancer Research Center, Division of Immunogenetics, Tumour Immunology Program, 69120 Heidelberg, Germany.
  • Zhang C; Institute of Pathology, Department of Surgical Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Fuller JC; Institute of Pathology, Department of Surgical Pathology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Wade RC; German Cancer Research Center, Clinical Cooperation Unit Molecular Tumor Pathology, 69120 Heidelberg, Germany.
  • Benner A; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), Department of Molecular and Cellular Modeling (MCM), 69118 Heidelberg, Germany.
  • Chang-Claude J; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), Department of Molecular and Cellular Modeling (MCM), 69118 Heidelberg, Germany.
  • Brenner H; Center for Molecular Biology (ZMBH), Molecular and Cellular Modeling (MCM), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg 69120, Germany.
  • Hoffmeister M; Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, 69120 Heidelberg, Germany.
  • Zentgraf H; German Cancer Research Center, Division of Biostatistics, 69120 Heidelberg, Germany.
  • Schirmacher P; Unit of Genetic Epidemiology, German Cancer Research Center, Division of Cancer Epidemiology, 69120 Heidelberg, Germany.
  • Roth W; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg- Eppendorf, 20246 Hamburg, Germany.
Nat Commun ; 7: 10764, 2016 Mar 07.
Article em En | MEDLINE | ID: mdl-26948869
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Proteína HMGB1 Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Proteína HMGB1 Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha