Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300.

Shrimp, Jonathan H; Sorum, Alexander W; Garlick, Julie M; Guasch, Laura; Nicklaus, Marc C; Meier, Jordan L

Shrimp, Jonathan H; Sorum, Alexander W; Garlick, Julie M; Guasch, Laura; Nicklaus, Marc C; Meier, Jordan L.

Afiliação

Shrimp JH; Chemical Biology Laboratory, National Cancer Institute , Frederick, Maryland 21702, United States.
Sorum AW; Chemical Biology Laboratory, National Cancer Institute , Frederick, Maryland 21702, United States.
Garlick JM; Chemical Biology Laboratory, National Cancer Institute , Frederick, Maryland 21702, United States.
Guasch L; Chemical Biology Laboratory, National Cancer Institute , Frederick, Maryland 21702, United States.
Nicklaus MC; Chemical Biology Laboratory, National Cancer Institute , Frederick, Maryland 21702, United States.
Meier JL; Chemical Biology Laboratory, National Cancer Institute , Frederick, Maryland 21702, United States.

ACS Med Chem Lett ; 7(2): 151-5, 2016 Feb 11.

Article em En | MEDLINE | ID: mdl-26985290

Palavras-chave

Acetylation; PAINS; acetyltransferase; epigenetics; pan-assay interference; probes; reversible covalent inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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