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Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions.
Poulsen, Christian Bo; Al-Mashhadi, Ahmed Ludvigsen; von Wachenfeldt, Karin; Bentzon, Jacob Fog; Nielsen, Lars Bo; Al-Mashhadi, Rozh H; Thygesen, Jesper; Tolbod, Lars; Larsen, Jens Rolighed; Frøkiær, Jørgen; Tawakol, Ahmed; Vucic, Esad; Fredrickson, Jill; Baruch, Amos; Frendéus, Björn; Robertson, Anna-Karin L; Moestrup, Søren Kragh; Drouet, Ludovic; Falk, Erling.
Afiliação
  • Poulsen CB; Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address: cbpoulsen@clin.au.dk.
  • Al-Mashhadi AL; Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • von Wachenfeldt K; Truly Translational, Lund, Sweden.
  • Bentzon JF; Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Nielsen LB; Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Al-Mashhadi RH; Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Thygesen J; Department of Clinical Engineering, Aarhus University Hospital, Aarhus, Denmark.
  • Tolbod L; Department of Nuclear Medicine and PET-Center, Aarhus University Hospital, Aarhus, Denmark.
  • Larsen JR; Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark.
  • Frøkiær J; Department of Nuclear Medicine and PET-Center, Aarhus University Hospital, Aarhus, Denmark.
  • Tawakol A; Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States.
  • Vucic E; Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States.
  • Fredrickson J; Genentech, Inc., San Francisco, United States.
  • Baruch A; Genentech, Inc., San Francisco, United States.
  • Frendéus B; BioInvent International AB, Lund, Sweden.
  • Robertson AK; BioInvent International AB, Lund, Sweden.
  • Moestrup SK; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • Drouet L; Department of Angiohematology, Hospital Lariboisiere, Paris, France.
  • Falk E; Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Int J Cardiol ; 215: 506-15, 2016 Jul 15.
Article em En | MEDLINE | ID: mdl-27135822
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Catepsinas / Aterosclerose / Hipercolesterolemia / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Qualitative_research Limite: Animals / Female / Humans Idioma: En Revista: Int J Cardiol Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Catepsinas / Aterosclerose / Hipercolesterolemia / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Qualitative_research Limite: Animals / Female / Humans Idioma: En Revista: Int J Cardiol Ano de publicação: 2016 Tipo de documento: Article