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The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration.
Dudek, Michal; Yang, Nan; Ruckshanthi, Jayalath Pd; Williams, Jack; Borysiewicz, Elzbieta; Wang, Ping; Adamson, Antony; Li, Jian; Bateman, John F; White, Michael R; Boot-Handford, Raymond P; Hoyland, Judith A; Meng, Qing-Jun.
Afiliação
  • Dudek M; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Yang N; Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, UK.
  • Ruckshanthi JP; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Williams J; Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, UK.
  • Borysiewicz E; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Wang P; Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, UK.
  • Adamson A; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Li J; Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, UK.
  • Bateman JF; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • White MR; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Boot-Handford RP; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Hoyland JA; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Meng QJ; Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Ann Rheum Dis ; 76(3): 576-584, 2017 Mar.
Article em En | MEDLINE | ID: mdl-27489225
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Degeneração do Disco Intervertebral / Fatores de Transcrição ARNTL / Proteínas Circadianas Period / Relógios Circadianos / Disco Intervertebral Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Degeneração do Disco Intervertebral / Fatores de Transcrição ARNTL / Proteínas Circadianas Period / Relógios Circadianos / Disco Intervertebral Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido