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Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia.
Masaki, Yukiko; Shimizu, Yoichi; Yoshioka, Takeshi; Feng, Fei; Zhao, Songji; Higashino, Kenichi; Numata, Yoshito; Kuge, Yuji.
Afiliação
  • Masaki Y; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Shimizu Y; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
  • Yoshioka T; Central Institute of Isotope Science, Hokkaido University, Sapporo, Japan.
  • Feng F; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Zhao S; Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Higashino K; Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Numata Y; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Kuge Y; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
PLoS One ; 11(8): e0161639, 2016.
Article em En | MEDLINE | ID: mdl-27580239
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Glutationa / Neoplasias Experimentais / Nitroimidazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Glutationa / Neoplasias Experimentais / Nitroimidazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão