HIC1 epigenetically represses CIITA transcription in B lymphocytes.

Zeng, Sheng; Yang, Yuyu; Cheng, Xian; Zhou, Bisheng; Li, Ping; Zhao, Yuhao; Kong, Xiaocen; Xu, Yong

Zeng, Sheng; Yang, Yuyu; Cheng, Xian; Zhou, Bisheng; Li, Ping; Zhao, Yuhao; Kong, Xiaocen; Xu, Yong.

Afiliação

Zeng S; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China.
Yang Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Cheng X; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China; Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Zhou B; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China.
Li P; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China; Department of Gastroenterology, Second Hospital Affiliated to Nanjing Medical University, Nanjing, China.
Zhao Y; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China.
Kong X; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China; Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: kongxiaocen2010@163.com.
Xu Y; Department of Pathophysiology, Key Laboratory of Cardiovascular Disease and Molecular Intervention, Nanjing Medical University, Nanjing, China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China. Electronic address: yjxu@njmu.edu.cn.

Biochim Biophys Acta ; 1859(12): 1481-1489, 2016 12.

Article em En | MEDLINE | ID: mdl-27720955

Assuntos

Linfócitos B/metabolismo; Fatores de Transcrição Kruppel-Like/biossíntese; Proteínas Nucleares/biossíntese; Transativadores/biossíntese; Transcrição Gênica; Diferenciação Celular/genética; DNA (Citosina-5-)-Metiltransferase 1; DNA (Citosina-5-)-Metiltransferases/antagonistas & inibidores; DNA (Citosina-5-)-Metiltransferases/genética; Epigênese Genética; Regulação da Expressão Gênica no Desenvolvimento; Humanos; Fatores de Transcrição Kruppel-Like/genética; Ativação Linfocitária/genética; Mutação; Proteínas Nucleares/genética; Regiões Promotoras Genéticas; Transativadores/genética; DNA Metiltransferase 3B

Palavras-chave

CIITA; DNMT; Epigenetics; HIC1; Transcriptional regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Proteínas Nucleares / Linfócitos B / Transativadores / Fatores de Transcrição Kruppel-Like Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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