Synthesis of macromolecular systems via lipase catalyzed biocatalytic reactions: applications and future perspectives.
Chem Soc Rev
; 45(24): 6855-6887, 2016 Dec 21.
Article
em En
| MEDLINE
| ID: mdl-27785498
ABSTRACT
Enzymes, being remarkable catalysts, are capable of accepting a wide range of complex molecules as substrates and catalyze a variety of reactions with a high degree of chemo-, stereo- and regioselectivity in most of the reactions. Biocatalysis can be used in both simple and complex chemical transformations without the need for tedious protection and deprotection chemistry that is very common in traditional organic synthesis. This current review highlights the applicability of one class of biocatalysts viz."lipases" in synthetic transformations, the resolution of pharmaceutically important small molecules including polyphenols, amides, nucleosides and their precursors, the development of macromolecular systems (and their applications as drug/gene carriers), flame retardants, polymeric antioxidants and nanocrystalline solar cells, etc.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Substâncias Macromoleculares
/
Biocatálise
/
Lipase
Limite:
Humans
Idioma:
En
Revista:
Chem Soc Rev
Ano de publicação:
2016
Tipo de documento:
Article