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Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder.
Di Salvo, J; Nagabukuro, H; Wickham, L A; Abbadie, C; DeMartino, J A; Fitzmaurice, A; Gichuru, L; Kulick, A; Donnelly, M J; Jochnowitz, N; Hurley, A L; Pereira, A; Sanfiz, A; Veronin, G; Villa, K; Woods, J; Zamlynny, B; Zycband, E; Salituro, G M; Frenkl, T; Weber, A E; Edmondson, S D; Struthers, M.
Afiliação
  • Di Salvo J; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey jerry.disalvo@evotec.com.
  • Nagabukuro H; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Wickham LA; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Abbadie C; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • DeMartino JA; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Fitzmaurice A; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Gichuru L; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Kulick A; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Donnelly MJ; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Jochnowitz N; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Hurley AL; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Pereira A; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Sanfiz A; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Veronin G; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Villa K; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Woods J; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Zamlynny B; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Zycband E; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Salituro GM; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Frenkl T; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Weber AE; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Edmondson SD; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
  • Struthers M; Discovery and Preclinical Sciences, Merck Research Laboratories, Kenilworth, New Jersey.
J Pharmacol Exp Ther ; 360(2): 346-355, 2017 02.
Article em En | MEDLINE | ID: mdl-27965369
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Pirrolidinas / Antagonistas Muscarínicos / Receptores Adrenérgicos beta 3 / Bexiga Urinária Hiperativa / Agonistas de Receptores Adrenérgicos beta 3 Limite: Animals / Female / Humans / Male Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Pirrolidinas / Antagonistas Muscarínicos / Receptores Adrenérgicos beta 3 / Bexiga Urinária Hiperativa / Agonistas de Receptores Adrenérgicos beta 3 Limite: Animals / Female / Humans / Male Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2017 Tipo de documento: Article