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Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis.
Mellone, Massimiliano; Hanley, Christopher J; Thirdborough, Steve; Mellows, Toby; Garcia, Edwin; Woo, Jeongmin; Tod, Joanne; Frampton, Steve; Jenei, Veronika; Moutasim, Karwan A; Kabir, Tasnuva D; Brennan, Peter A; Venturi, Giulia; Ford, Kirsty; Herranz, Nicolas; Lim, Kue Peng; Clarke, James; Lambert, Daniel W; Prime, Stephen S; Underwood, Timothy J; Vijayanand, Pandurangan; Eliceiri, Kevin W; Woelk, Christopher; King, Emma V; Gil, Jesus; Ottensmeier, Christian H; Thomas, Gareth J.
Afiliação
  • Mellone M; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Hanley CJ; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Thirdborough S; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Mellows T; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Garcia E; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Woo J; Faculty of Medicine, University of Southampton, Southampton SO166YD, UK.
  • Tod J; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Frampton S; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Jenei V; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Moutasim KA; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Kabir TD; Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield S102TA, UK.
  • Brennan PA; Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, Portsmouth PO63LY, UK.
  • Venturi G; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Ford K; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Herranz N; MRC Clinical Sciences Centre, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, London W12, UK.
  • Lim KP; Cancer Research Initiatives Foundation. Sime Darby Medical Centre, Subang Jaya, Selangor 47500, Malaysia.
  • Clarke J; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Lambert DW; Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield S102TA, UK.
  • Prime SS; Centre for Clinical and Diagnostic Oral Sciences, Institute of Dentistry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E12AD, UK.
  • Underwood TJ; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Vijayanand P; La Jolla Institute for Allergy & Immunology, La Jolla, California 92037, USA.
  • Eliceiri KW; Laboratory for Optical and Computational Instrumentation (LOCI), Department of Biomedical Engineering, University of Madison, Wisconsin, WI 53706, USA.
  • Woelk C; Faculty of Medicine, University of Southampton, Southampton SO166YD, UK.
  • King EV; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Gil J; MRC Clinical Sciences Centre, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, London W12, UK.
  • Ottensmeier CH; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
  • Thomas GJ; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO166YD, UK.
Aging (Albany NY) ; 9(1): 114-132, 2016 12 15.
Article em En | MEDLINE | ID: mdl-27992856
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Senescência Celular / Miofibroblastos / Fibroblastos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Aging (Albany NY) Assunto da revista: GERIATRIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Senescência Celular / Miofibroblastos / Fibroblastos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Aging (Albany NY) Assunto da revista: GERIATRIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido