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The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.
Loubiere, Camille; Clavel, Stephan; Gilleron, Jerome; Harisseh, Rania; Fauconnier, Jeremy; Ben-Sahra, Issam; Kaminski, Lisa; Laurent, Kathiane; Herkenne, Stephanie; Lacas-Gervais, Sandra; Ambrosetti, Damien; Alcor, Damien; Rocchi, Stephane; Cormont, Mireille; Michiels, Jean-François; Mari, Bernard; Mazure, Nathalie M; Scorrano, Luca; Lacampagne, Alain; Gharib, Abdallah; Tanti, Jean-François; Bost, Frederic.
Afiliação
  • Loubiere C; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
  • Clavel S; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Gilleron J; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
  • Harisseh R; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Fauconnier J; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
  • Ben-Sahra I; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Kaminski L; Inserm U1060/ INRA 1235/ Université-Lyon1/ INSA, Lyon, France.
  • Laurent K; Inserm U1046, UMR CNRS 9214, Université de Montpellier, Montpellier, France.
  • Herkenne S; Northwestern University, Chicago, IL, USA.
  • Lacas-Gervais S; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
  • Ambrosetti D; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Alcor D; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
  • Rocchi S; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Cormont M; Department of Biology, University of Padua, Padua, Italy.
  • Michiels JF; Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Padua, Italy.
  • Mari B; Centre Commun de Microscopie Appliquée, Université de Nice Sophia-Antipolis, Nice, France.
  • Mazure NM; Centre Hospitalier Universitaire (CHU) de Nice, Hôpital Pasteur, Laboratoire Central d'Anatomo Pathologie, 06002, Nice, France.
  • Scorrano L; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
  • Lacampagne A; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Gharib A; Université Nice Côte d'Azur, Inserm, Nice, France.
  • Tanti JF; Inserm U1065, C3M, Team Biology and pathology of melanocyte cells: From skin pigmentation to melanomas, Nice, France.
  • Bost F; Inserm U1065, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France.
Sci Rep ; 7(1): 5040, 2017 07 11.
Article em En | MEDLINE | ID: mdl-28698627
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio / Metabolismo Energético / Metformina / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio / Metabolismo Energético / Metformina / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França