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Trajectories in Leisure-Time Physical Activity and Risk of Stroke in Women in the California Teachers Study.
Willey, Joshua Z; Voutsinas, Jenna; Sherzai, Ayesha; Ma, Huiyan; Bernstein, Leslie; Elkind, Mitchell S V; Cheung, Ying K; Wang, Sophia S.
Afiliação
  • Willey JZ; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Voutsinas J; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Sherzai A; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Ma H; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Bernstein L; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Elkind MSV; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Cheung YK; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
  • Wang SS; From the Departments of Neurology (J.Z.W., M.S.V.E.), Epidemiology (M.S.V.E.), and Biostatistics (Y.K.C.), Columbia University, New York; Department of Population Sciences, City of Hope, Duarte, CA (J.V., H.M., L.B., S.S.W.); and Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA
Stroke ; 48(9): 2346-2352, 2017 09.
Article em En | MEDLINE | ID: mdl-28794273
ABSTRACT
BACKGROUND AND

PURPOSE:

Whether changes in leisure-time physical activity (LTPA) over time are associated with lower risk of stroke is not well established. We examined the association between changes in self-reported LTPA 10 years apart, with risk of incident stroke in the CTS (California Teachers Study). We hypothesized that the risk of stroke would be lowest among those who remained active.

METHODS:

Sixty-one thousand two hundred and fifty-six CTS participants reported LTPA at 2 intensity levels (moderate and strenuous activity) at 2 time points (baseline 1995-96; 10-year follow-up 2005-2006). LTPA at each intensity level was categorized based on American Heart Association (AHA) recommendations (moderate, >150 minutes/week; strenuous, >75 minutes/week). Changes in LTPA were summarized as follows (1) not meeting recommendations at both time points; (2) meeting recommendations only at follow-up; (3) meeting recommendations only at baseline; and (4) meeting recommendations at both time points. Incident strokes were identified through California state hospitalization records. Using multivariable Cox models, we examined the associations between changes in LTPA with incident stroke.

RESULTS:

Nine hundred and eighty-seven women were diagnosed with stroke who completed both questionnaires. Meeting AHA recommendations at both the time points was associated with a lower risk of all stroke (adjusted hazard ratio, 0.84; 95% confidence interval, 0.72-0.98). The protective effects for stroke were driven by meeting AHA recommendations for moderate activity and largely observed for ischemic strokes (adjusted hazard ratio, 0.70; 95% confidence interval, 0.55-0.88).

CONCLUSIONS:

Meeting AHA recommendations for moderate activity had a protective effect for reducing ischemic stroke risk. Participants who met AHA recommendations at baseline but not at follow-up, however, were not afforded reduced stroke risk.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exercício Físico / Acidente Vascular Cerebral / Atividades de Lazer Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Stroke Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exercício Físico / Acidente Vascular Cerebral / Atividades de Lazer Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Stroke Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá