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Blockade of surface-bound TGF-ß on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.
Budhu, Sadna; Schaer, David A; Li, Yongbiao; Toledo-Crow, Ricardo; Panageas, Katherine; Yang, Xia; Zhong, Hong; Houghton, Alan N; Silverstein, Samuel C; Merghoub, Taha; Wolchok, Jedd D.
Afiliação
  • Budhu S; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Schaer DA; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Li Y; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Toledo-Crow R; Research Engineering Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Panageas K; Research Engineering Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Yang X; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Zhong H; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Houghton AN; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Silverstein SC; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Merghoub T; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Wolchok JD; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Sci Signal ; 10(494)2017 Aug 29.
Article em En | MEDLINE | ID: mdl-28851824
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Terapia de Imunossupressão / Linfócitos T Reguladores / Linfócitos T CD8-Positivos / Microambiente Tumoral Limite: Animals Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Terapia de Imunossupressão / Linfócitos T Reguladores / Linfócitos T CD8-Positivos / Microambiente Tumoral Limite: Animals Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos