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[Quality evaluation of decoction of single medicinal herb--a case of Lonicerae Japinicae Flos].
Dai, Yun-Tao; Li, Qi; Fan, Zi-Quan; Wang, Dan-Dan; Dong, Qing; Tong, Jia-Yu; Takehisa, Tomada; Chen, Shi-Lin.
Afiliação
  • Dai YT; Institute of Chinese Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China.
  • Li Q; Shanghai Traditional Chinese Medicine Co., Ltd., Shanghai 200002, China.
  • Fan ZQ; Waters Corporation(Shanghai), Shanghai 201206, China.
  • Wang DD; Waters Corporation(Shanghai), Shanghai 201206, China.
  • Dong Q; Institute of Chinese Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China.
  • Tong JY; Institute of Chinese Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China.
  • Takehisa T; Botanical Raw Materials Research Department, Tsumura & Co., Tokyo 107-8521, Japan.
  • Chen SL; Institute of Chinese Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi ; 42(5): 809-816, 2017 Mar.
Article em Zh | MEDLINE | ID: mdl-28994518
ABSTRACT
Decoction of single medicinal herb is a reference for the standardization of different dosage form of Chinese medicine and it provides a new direction for solving the problems existing in the quality of Chinese medicinal granules such no uniform dosage forms and no clear quality standard. There are few reports on the idea, method and preparation of single herb standard decoction. Our country is in urgent need of that information in order to improve the consistency and stability of traditional Chinese medicine products. Here, Lonicerae Japinicae Flos was selected as an example to elucidate the preparation and quality evaluation of Chinese single herbal medicine decoction. Twelve batches of representative Lonicerae Japinicae Flos were collected, UPLC fingerprints were established, and the chemical structures of main peaks were identified with UPLC-QTOF-MS and standard compounds. The main components in the decoction are organic acids and iridoids. The extract rate of the standard decoction was (34.2±2.9)% and the transfer rate is (78.6±8.4)% in the form of chlorogenic acid, within the range of 75%-125% of mean. This paper established a method for the quality evaluation of standard decoction of Lonicerae Japinicae Flos and provided reference for the quality control method of terminal products from decoction of Lonicerae Japinicae Flos.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Lonicera Tipo de estudo: Prognostic_studies Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Lonicera Tipo de estudo: Prognostic_studies Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China