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Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains.
Zost, Seth J; Parkhouse, Kaela; Gumina, Megan E; Kim, Kangchon; Diaz Perez, Sebastian; Wilson, Patrick C; Treanor, John J; Sant, Andrea J; Cobey, Sarah; Hensley, Scott E.
Afiliação
  • Zost SJ; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Parkhouse K; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Gumina ME; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Kim K; Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637.
  • Diaz Perez S; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Wilson PC; Department of Medicine, University of Chicago, Chicago, IL 60637.
  • Treanor JJ; Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642.
  • Sant AJ; Department of Microbiology and Immunology, David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
  • Cobey S; Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637.
  • Hensley SE; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; hensley@pennmedicine.upenn.edu.
Proc Natl Acad Sci U S A ; 114(47): 12578-12583, 2017 11 21.
Article em En | MEDLINE | ID: mdl-29109276
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Vírus da Influenza A Subtipo H3N2 / Anticorpos Antivirais / Antígenos Virais Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Vírus da Influenza A Subtipo H3N2 / Anticorpos Antivirais / Antígenos Virais Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article