Hypolipidemic activity and mechanisms of the total phenylpropanoid glycosides from Ligustrum robustum (Roxb.) Blume by AMPK-SREBP-1c pathway in hamsters fed a high-fat diet.

Yang, Runmei; Chu, Xinxin; Sun, Le; Kang, Zhuoying; Ji, Min; Yu, Ying; Liu, Ying; He, Zhendan; Gao, Nannan

Yang, Runmei; Chu, Xinxin; Sun, Le; Kang, Zhuoying; Ji, Min; Yu, Ying; Liu, Ying; He, Zhendan; Gao, Nannan.

Afiliação

Yang R; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Chu X; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Sun L; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Kang Z; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Ji M; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Yu Y; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Liu Y; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
He Z; Department of Pharmacy, School of Medicine, Shenzhen University, Shenzhen, 518060, China.
Gao N; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education; Pharmacology and Toxicology Research Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.

Phytother Res ; 32(4): 715-722, 2018 Apr.

Article em En | MEDLINE | ID: mdl-29468762

Assuntos

Dieta Hiperlipídica/métodos; Glicosídeos/química; Ligustrum/química; Metabolismo dos Lipídeos/efeitos dos fármacos; Extratos Vegetais/química; Animais; Cricetinae; Masculino; Proteína de Ligação a Elemento Regulador de Esterol 1/metabolismo

Palavras-chave

AMP-activated protein kinase (AMPK); hamster; hyperlipidemia; sterol regulatory element binding protein-1c (SREBP-1c); total phenylpropanoid glycoside from Ligustrum robustum (Roxb.) Blume (LRTPG); triglyceride

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Ligustrum / Metabolismo dos Lipídeos / Dieta Hiperlipídica / Glicosídeos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Phytother Res Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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