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Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles.
Sutherland, Hamish S; Tong, Amy S T; Choi, Peter J; Conole, Daniel; Blaser, Adrian; Franzblau, Scott G; Cooper, Christopher B; Upton, Anna M; Lotlikar, Manisha U; Denny, William A; Palmer, Brian D.
Afiliação
  • Sutherland HS; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Tong AST; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Conole D; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Blaser A; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Cooper CB; Global Alliance for TB Drug Development, 40 Wall St, New York, NY 10005, USA.
  • Upton AM; Global Alliance for TB Drug Development, 40 Wall St, New York, NY 10005, USA.
  • Lotlikar MU; Global Alliance for TB Drug Development, 40 Wall St, New York, NY 10005, USA.
  • Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address: b.denny@auckland.ac.nz.
  • Palmer BD; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Bioorg Med Chem ; 26(8): 1797-1809, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29482950

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Bicíclicos Heterocíclicos com Pontes / Diarilquinolinas / Mycobacterium tuberculosis / Naftalenos / Antituberculosos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Nova Zelândia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Bicíclicos Heterocíclicos com Pontes / Diarilquinolinas / Mycobacterium tuberculosis / Naftalenos / Antituberculosos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Nova Zelândia