Pharmacokinetics and Metabolism of Streptochlorin and Its Synthetic Derivative, 5-Hydroxy-2'-isobutyl Streptochlorin, in Mice.

Zhou, Yuanyuan; Choi, Yeon Jung; Kim, Eunyeong; Oh, Mun Hwan; Shin, Hee Jae; Kim, Sang Kyum; Lee, Kiho

Zhou, Yuanyuan; Choi, Yeon Jung; Kim, Eunyeong; Oh, Mun Hwan; Shin, Hee Jae; Kim, Sang Kyum; Lee, Kiho.

Afiliação

Zhou Y; College of Pharmacy, Korea University.
Choi YJ; College of Pharmacy, Chungnam National University.
Kim E; College of Pharmacy, Korea University.
Oh MH; College of Pharmacy, Korea University.
Shin HJ; Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology (KIOST).
Kim SK; College of Pharmacy, Chungnam National University.
Lee K; College of Pharmacy, Korea University.

Biol Pharm Bull ; 41(3): 326-337, 2018.

Article em En | MEDLINE | ID: mdl-29491209

Assuntos

Antibacterianos/farmacocinética; Indóis/farmacocinética; Oxazóis/farmacocinética; Administração Intravenosa; Animais; Antibacterianos/metabolismo; Área Sob a Curva; Disponibilidade Biológica; Biotransformação; Glucuronídeos/metabolismo; Meia-Vida; Indóis/metabolismo; Fígado/metabolismo; Masculino; Membranas Artificiais; Camundongos; Camundongos Endogâmicos ICR; Microssomos Hepáticos/metabolismo; Oxazóis/metabolismo; Frações Subcelulares/metabolismo

Palavras-chave

5-hydroxy-2'-isobutyl streptochlorin; metabolism; pharmacokinetics; streptochlorin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazóis / Indóis / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biol Pharm Bull Assunto da revista: BIOQUIMICA / FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article

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