Advances in extracellular ligand recognition sites on prostanoid receptors.

Li, Yan; Xu, Anna; Ling, Qinglan; Ruan, Ke-He

Li, Yan; Xu, Anna; Ling, Qinglan; Ruan, Ke-He.

Afiliação

Li Y; The Center for Experimental Therapeutics & Pharmacoinformatics, Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Xu A; The Center for Experimental Therapeutics & Pharmacoinformatics, Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Ling Q; The Center for Experimental Therapeutics & Pharmacoinformatics, Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Ruan KH; The Center for Experimental Therapeutics & Pharmacoinformatics, Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.

Future Med Chem ; 10(9): 979-981, 2018 05 01.

Article em En | MEDLINE | ID: mdl-29673264

Assuntos

Descoberta de Drogas; Receptores de Prostaglandina/metabolismo; Animais; Humanos; Ligantes; Prostaglandinas/metabolismo; Receptores de Prostaglandina/química

Palavras-chave

3D computational receptor model; COX-1; COX-2; EP3; IP; TP; ligand recognition site; prostanoids; site-directed mutagenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Prostaglandina / Descoberta de Drogas Limite: Animals / Humans Idioma: En Revista: Future Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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