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Hepatitis D Viremia Among Injection Drug Users in San Francisco.
Mahale, Parag; Aka, Peter V; Chen, Xiaohua; Liu, Ping; Fram, Benjamin J; Wang, Alan S; Simenel, Scott; Tseng, Fan-Chen; Chen, Sabrina; Edlin, Brian R; Glenn, Jeffrey S; O'Brien, Thomas R.
Afiliação
  • Mahale P; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.
  • Aka PV; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.
  • Chen X; Demographic and Health Surveys, ICF International, Rockville, Maryland.
  • Liu P; Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
  • Fram BJ; Department of Infectious Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, China.
  • Wang AS; Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
  • Simenel S; Department of Microbiology and Immunology, Stanford University School of Medicine, Palo Alto, California.
  • Tseng FC; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.
  • Chen S; Department of Microbiology and Immunology, Stanford University School of Medicine, Palo Alto, California.
  • Edlin BR; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.
  • Glenn JS; Information Management Services, Calverton, Maryland.
  • O'Brien TR; Urban Health Study, University of California San Francisco.
J Infect Dis ; 217(12): 1902-1906, 2018 05 25.
Article em En | MEDLINE | ID: mdl-29800369
ABSTRACT
People who inject drugs (PWID) are commonly exposed to hepatitis B virus (HBV) and hepatitis D virus (HDV). We evaluated the prevalence of HDV viremia among hepatitis B surface antigen (HBsAg)-positive PWID (n = 73) using a new quantitative microarray antibody capture (Q-MAC) assay, HDV western blot, and HDV RNA. HDV Q-MAC performed well in this cohort anti-HDV, 100% sensitivity and specificity; HDV viremia, 61.5% sensitivity and 100% specificity. Hepatitis D viremia was present in 35.6% of HBsAg-positive participants and was more common in those with resolved compared to chronic hepatitis C (5.1% vs 0.6%; adjusted odds ratio, 9.80; P < .0001).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Viremia / Hepatite D / Abuso de Substâncias por Via Intravenosa Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: J Infect Dis Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Viremia / Hepatite D / Abuso de Substâncias por Via Intravenosa Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: J Infect Dis Ano de publicação: 2018 Tipo de documento: Article