Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts.

Reeves, Stephen R; Kang, Inkyung; Chan, Christina K; Barrow, Kaitlyn A; Kolstad, Tessa K; White, Maria P; Ziegler, Steven F; Wight, Thomas N; Debley, Jason S

Reeves, Stephen R; Kang, Inkyung; Chan, Christina K; Barrow, Kaitlyn A; Kolstad, Tessa K; White, Maria P; Ziegler, Steven F; Wight, Thomas N; Debley, Jason S.

Afiliação

Reeves SR; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA, 98105, USA. stephen.reeves@seattlechildrens.org.
Kang I; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA. stephen.reeves@seattlechildrens.org.
Chan CK; Department of Pediatrics, University of Washington, Seattle, WA, USA. stephen.reeves@seattlechildrens.org.
Barrow KA; Matrix Biology Program, Benaroya Research Institute, Seattle, WA, USA.
Kolstad TK; Matrix Biology Program, Benaroya Research Institute, Seattle, WA, USA.
White MP; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.
Ziegler SF; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.
Wight TN; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.
Debley JS; Immunology Program, Benaroya Research Institute, Seattle, WA, USA.

Respir Res ; 19(1): 146, 2018 08 02.

Article em En | MEDLINE | ID: mdl-30071849

Assuntos

Asma/metabolismo; Brônquios/metabolismo; Matriz Extracelular/metabolismo; Ácido Hialurônico/biossíntese; Leucócitos/metabolismo; Mucosa Respiratória/metabolismo; Adolescente; Brônquios/citologia; Criança; Técnicas de Cocultura; Feminino; Fibroblastos/metabolismo; Humanos; Pulmão/metabolismo; Masculino; Mucosa Respiratória/citologia; Células U937

Palavras-chave

Airway inflammation; Airway remodeling; Asthma; Children; Epithelial cells; Extracellular matrix; Human lung fibroblasts; Hyaluronan

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Brônquios / Mucosa Respiratória / Matriz Extracelular / Ácido Hialurônico / Leucócitos Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Respir Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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