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SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.
Kmiec, Dorota; Akbil, Bengisu; Ananth, Swetha; Hotter, Dominik; Sparrer, Konstantin M J; Stürzel, Christina M; Trautz, Birthe; Ayouba, Ahidjo; Peeters, Martine; Yao, Zhong; Stagljar, Igor; Passos, Vânia; Zillinger, Thomas; Goffinet, Christine; Sauter, Daniel; Fackler, Oliver T; Kirchhoff, Frank.
Afiliação
  • Kmiec D; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Akbil B; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Ananth S; Department of Infectious Diseases, Integrative Virology, CIID, University Hospital Heidelberg, Heidelberg, Germany.
  • Hotter D; German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.
  • Sparrer KMJ; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Stürzel CM; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Trautz B; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Ayouba A; Department of Infectious Diseases, Integrative Virology, CIID, University Hospital Heidelberg, Heidelberg, Germany.
  • Peeters M; German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.
  • Yao Z; TransVIHMI, Institut de Recherche pour le Développement, University of Montpellier, INSERM, Montpellier, France.
  • Stagljar I; TransVIHMI, Institut de Recherche pour le Développement, University of Montpellier, INSERM, Montpellier, France.
  • Passos V; Donnelly Centre, University of Toronto, Ontario, Canada.
  • Zillinger T; Donnelly Centre, University of Toronto, Ontario, Canada.
  • Goffinet C; Departments of Biochemistry and Molecular Genetics, University of Toronto, Ontario, Canada.
  • Sauter D; Institute of Virology, Hannover Medical School, Hannover, Germany.
  • Fackler OT; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn, Bonn, Germany.
  • Kirchhoff F; Institute of Virology, Hannover Medical School, Hannover, Germany.
PLoS Pathog ; 14(8): e1007269, 2018 08.
Article em En | MEDLINE | ID: mdl-30125328
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação Viral / Linfócitos T CD4-Positivos / Produtos do Gene nef / HIV-1 / Tecido Linfoide / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação Viral / Linfócitos T CD4-Positivos / Produtos do Gene nef / HIV-1 / Tecido Linfoide / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha