MicroRNA-140-5p targeting tumor necrosis factor-&#945; prevents pulmonary arterial hypertension.

Zhu, Tian-Tian; Zhang, Wei-Fang; Yin, Ya-Ling; Liu, Yu-Hao; Song, Ping; Xu, Jian; Zhang, Ming-Xiang; Li, Peng

MicroRNA-140-5p targeting tumor necrosis factor-α prevents pulmonary arterial hypertension.

Zhu, Tian-Tian; Zhang, Wei-Fang; Yin, Ya-Ling; Liu, Yu-Hao; Song, Ping; Xu, Jian; Zhang, Ming-Xiang; Li, Peng.

Afiliação

Zhu TT; Teaching and Research Office of Clinical Pharmacology, College of Pharmacy, Xinxiang Medical University, Xinxiang, China.
Zhang WF; Department of Pharmacy, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Yin YL; Teaching and Research Office of Physiology and Neurobiology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China.
Liu YH; Teaching and Research Office of Clinical Pharmacology, College of Pharmacy, Xinxiang Medical University, Xinxiang, China.
Song P; Teaching and Research Office of Clinical Pharmacology, College of Pharmacy, Xinxiang Medical University, Xinxiang, China.
Xu J; Teaching and Research Office of Clinical Pharmacology, College of Pharmacy, Xinxiang Medical University, Xinxiang, China.
Zhang MX; Teaching and Research Office of Clinical Pharmacology, College of Pharmacy, Xinxiang Medical University, Xinxiang, China.
Li P; Teaching and Research Office of Clinical Pharmacology, College of Pharmacy, Xinxiang Medical University, Xinxiang, China.

J Cell Physiol ; 234(6): 9535-9550, 2019 06.

Article em En | MEDLINE | ID: mdl-30367500

Assuntos

MicroRNAs/metabolismo; Hipertensão Arterial Pulmonar/genética; Hipertensão Arterial Pulmonar/prevenção & controle; Fator de Necrose Tumoral alfa/genética; Animais; Antagomirs; Sequência de Bases; Hipóxia Celular/genética; Movimento Celular/genética; Proliferação de Células/genética; Modelos Animais de Doenças; Regulação para Baixo/genética; Células HEK293; Humanos; Masculino; MicroRNAs/genética; Monocrotalina; Miócitos de Músculo Liso/metabolismo; Fenótipo; Ratos Sprague-Dawley; Transdução de Sinais/genética; Fator de Necrose Tumoral alfa/metabolismo; Regulação para Cima/genética

Palavras-chave

TNF-α; hypoxia; miR-140-5p; pulmonary arterial hypertension

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Necrose Tumoral alfa / MicroRNAs / Hipertensão Arterial Pulmonar Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Cell Physiol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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