[Enhancing Antitumor Effects Using Hyperthermia(Including Immune Checkpoint Inhibitor)].
Gan To Kagaku Ryoho
; 45(10): 1479-1481, 2018 Oct.
Article
em Ja
| MEDLINE
| ID: mdl-30382051
ABSTRACT
Hyperthermia enhances the efficacies of radiotherapy, chemotherapy, immunotherapy, and molecular targeted therapy. In this study, we investigated whether hyperthermia enhanced the efficacy of immune check point inhibitor therapy. The LLC tumor inoculated in mouse was heated and immunostained, which showed increase in PD-L1 staining post-heating. PD-L1 and HLA class I staining increased after heating samples derived from a case of analinvasion of rectalcancer associated with Lynch syndrome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipertermia Induzida
/
Neoplasias
Limite:
Animals
/
Humans
/
Male
/
Middle aged
Idioma:
Ja
Revista:
Gan To Kagaku Ryoho
Ano de publicação:
2018
Tipo de documento:
Article