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Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer.
Jayson, Gordon C; Zhou, Cong; Backen, Alison; Horsley, Laura; Marti-Marti, Kalena; Shaw, Danielle; Mescallado, Nerissa; Clamp, Andrew; Saunders, Mark P; Valle, Juan W; Mullamitha, Saifee; Braun, Mike; Hasan, Jurjees; McEntee, Delyth; Simpson, Kathryn; Little, Ross A; Watson, Yvonne; Cheung, Susan; Roberts, Caleb; Ashcroft, Linda; Manoharan, Prakash; Scherer, Stefan J; Del Puerto, Olivia; Jackson, Alan; O'Connor, James P B; Parker, Geoff J M; Dive, Caroline.
Afiliação
  • Jayson GC; The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, M20 4BX, UK. Gordon.Jayson@manchester.ac.uk.
  • Zhou C; Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester, M20 4GJ, UK.
  • Backen A; Clinical and Experimental Pharmacology Group, Cancer Research UK Manchester Institute & Manchester Centre for Cancer Biomarker Sciences, Manchester, M20 4BX, UK.
  • Horsley L; The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, M20 4BX, UK.
  • Marti-Marti K; The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, M20 4BX, UK.
  • Shaw D; Clatterbridge Cancer Centre, Liverpool, CH63 4JY, UK.
  • Mescallado N; The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, M20 4BX, UK.
  • Clamp A; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • Saunders MP; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • Valle JW; The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, M20 4BX, UK.
  • Mullamitha S; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • Braun M; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • Hasan J; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • McEntee D; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • Simpson K; Clinical and Experimental Pharmacology Group, Cancer Research UK Manchester Institute & Manchester Centre for Cancer Biomarker Sciences, Manchester, M20 4BX, UK.
  • Little RA; Imaging Sciences, University of Manchester, Manchester, M13 9PT, UK.
  • Watson Y; Imaging Sciences, University of Manchester, Manchester, M13 9PT, UK.
  • Cheung S; Imaging Sciences, University of Manchester, Manchester, M13 9PT, UK.
  • Roberts C; Imaging Sciences, University of Manchester, Manchester, M13 9PT, UK.
  • Ashcroft L; Manchester Academic Health Science Centre, Trials Co-ordination Unit, The Christie NHS Foundation Trust, Withington Hall Block C, Wilmslow Road, Manchester, M20 4BX, UK.
  • Manoharan P; The Christie NHS Foundation Trust and Division of Cancer Sciences, University of Manchester, Manchester, M20 4BX, UK.
  • Scherer SJ; Novartis Pharmaceuticals Corporation, One Health Plaza, 337, East Hanover, NJ, 07936-1080, USA.
  • Del Puerto O; Del Puerto Limited, 23 Porters Wood; Saint Albans, Hertfordshire, AL3 6PQ, UK.
  • Jackson A; Imaging Sciences, University of Manchester, Manchester, M13 9PT, UK.
  • O'Connor JPB; Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester, M20 4GJ, UK.
  • Parker GJM; Imaging Sciences, University of Manchester, Manchester, M13 9PT, UK.
  • Dive C; Bioxydyn Ltd, Manchester, M15 6SZ, UK.
Nat Commun ; 9(1): 4672, 2018 11 07.
Article em En | MEDLINE | ID: mdl-30405103
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Inibidores da Angiogênese / Receptor TIE-2 / Fator A de Crescimento do Endotélio Vascular Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Inibidores da Angiogênese / Receptor TIE-2 / Fator A de Crescimento do Endotélio Vascular Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido