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A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia.
Döhner, Hartmut; Müller-Tidow, Carsten; Lübbert, Michael; Fiedler, Walter; Krämer, Alwin; Westermann, Jörg; Bug, Gesine; Schlenk, Richard F; Krug, Utz; Goeldner, Rainer-Georg; Hilbert, James; Taube, Tillmann; Ottmann, Oliver G.
Afiliação
  • Döhner H; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
  • Müller-Tidow C; Department of Medicine A, University Hospital Muenster, Muenster, Germany.
  • Lübbert M; Department of Haematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Centre, Faculty of Medicine, Freiburg, Germany.
  • Fiedler W; Department of Medicine II, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Krämer A; Department of Internal Medicine V, University of Heidelberg and German Cancer Research Centre (DKFZ), Heidelberg, Germany.
  • Westermann J; Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité - Universitaetsmedizin Berlin, Berlin, Germany.
  • Bug G; Department of Medicine, Haematology/Oncology, Goethe University, Frankfurt/Main, Germany.
  • Schlenk RF; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
  • Krug U; Department of Medicine A, University Hospital Muenster, Muenster, Germany.
  • Goeldner RG; Biostatistics and Data Sciences, Boehringer Ingelheim International GmbH, Biberach, Germany.
  • Hilbert J; Clinical Pharmacokinetics/Pharmacodynamics, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
  • Taube T; Medicine Therapeutic Area Oncology, Boehringer Ingelheim International GmbH, Biberach, Germany.
  • Ottmann OG; Department of Medicine, Haematology/Oncology, Goethe University, Frankfurt/Main, Germany.
Br J Haematol ; 185(3): 583-587, 2019 05.
Article em En | MEDLINE | ID: mdl-30450591
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Protocolos de Quimioterapia Combinada Antineoplásica / Aurora Quinase B / Proteínas de Neoplasias Tipo de estudo: Clinical_trials Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Protocolos de Quimioterapia Combinada Antineoplásica / Aurora Quinase B / Proteínas de Neoplasias Tipo de estudo: Clinical_trials Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha