Functional Selectivity and Partial Efficacy at the Monoamine Transporters: A Unified Model of Allosteric Modulation and Amphetamine-Induced Substrate Release.

Hasenhuetl, Peter S; Bhat, Shreyas; Freissmuth, Michael; Sandtner, Walter

Hasenhuetl, Peter S; Bhat, Shreyas; Freissmuth, Michael; Sandtner, Walter.

Afiliação

Hasenhuetl PS; Institute of Pharmacology, Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Bhat S; Institute of Pharmacology, Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Freissmuth M; Institute of Pharmacology, Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria michael.freissmuth@meduniwien.ac.at.
Sandtner W; Institute of Pharmacology, Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

Mol Pharmacol ; 95(3): 303-312, 2019 03.

Article em En | MEDLINE | ID: mdl-30567955

Assuntos

Regulação Alostérica/efeitos dos fármacos; Anfetamina/farmacologia; Transporte Biológico/efeitos dos fármacos; Dopamina/metabolismo; Humanos; Cinética; Norepinefrina/metabolismo; Serotonina/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transporte Biológico / Regulação Alostérica / Anfetamina Limite: Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Áustria

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