Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors.

Heinhuis, K M; Ros, W; Kok, M; Steeghs, N; Beijnen, J H; Schellens, J H M

Heinhuis, K M; Ros, W; Kok, M; Steeghs, N; Beijnen, J H; Schellens, J H M.

Afiliação

Heinhuis KM; Divisions of Pharmacology, Utrecht University, Utrecht, The Netherlands.
Ros W; Divisions of Pharmacology, Utrecht University, Utrecht, The Netherlands.
Kok M; Medical Oncology and Molecular Oncology & Immunology, Utrecht University, Utrecht, The Netherlands.
Steeghs N; Medical Oncology, Department of Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.
Beijnen JH; Divisions of Pharmacology, Utrecht University, Utrecht, The Netherlands; Department of Pharmacy, The Netherlands Cancer Institute, Amsterdam, The Netherlands; MC Slotervaart, Amsterdam, The Netherlands; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Schellens JHM; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. Electronic address: j.schellens@gmail.com.

Ann Oncol ; 30(2): 219-235, 2019 02 01.

Article em En | MEDLINE | ID: mdl-30608567

Assuntos

Antineoplásicos Imunológicos/uso terapêutico; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Imunoterapia/métodos; Neoplasias/tratamento farmacológico; Microambiente Tumoral/imunologia; Pontos de Checagem do Ciclo Celular/efeitos dos fármacos; Quimioterapia Combinada; Humanos; Neoplasias/imunologia; Neoplasias/patologia; Prognóstico; Microambiente Tumoral/efeitos dos fármacos

Palavras-chave

cancer; checkpoint inhibitors; chemoimmunotherapy; chemotherapy; neoplasms

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Microambiente Tumoral / Antineoplásicos Imunológicos / Imunoterapia / Neoplasias Tipo de estudo: Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda

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