Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.

Gaugg, Martin Thomas; Engler, Anna; Bregy, Lukas; Nussbaumer-Ochsner, Yvonne; Eiffert, Lara; Bruderer, Tobias; Zenobi, Renato; Sinues, Pablo; Kohler, Malcolm

Gaugg, Martin Thomas; Engler, Anna; Bregy, Lukas; Nussbaumer-Ochsner, Yvonne; Eiffert, Lara; Bruderer, Tobias; Zenobi, Renato; Sinues, Pablo; Kohler, Malcolm.

Afiliação

Gaugg MT; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland.
Engler A; Department of Pulmonology, University Hospital of Zurich, Zurich, Switzerland.
Bregy L; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland.
Nussbaumer-Ochsner Y; Department of Pulmonology, University Hospital of Zurich, Zurich, Switzerland.
Eiffert L; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland.
Bruderer T; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland.
Zenobi R; Division of Respiratory Medicine, Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Sinues P; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland.
Kohler M; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland.

Respirology ; 24(5): 437-444, 2019 05.

Article em En | MEDLINE | ID: mdl-30681243

Assuntos

Aminoácidos/metabolismo; Testes Respiratórios/métodos; Fibrose Pulmonar Idiopática/diagnóstico; Fibrose Pulmonar Idiopática/metabolismo; Idoso; Alanina/metabolismo; Área Sob a Curva; Biomarcadores/metabolismo; Estudos de Casos e Controles; Progressão da Doença; Expiração; Feminino; Humanos; Hidroxiprolina/metabolismo; Isoleucina/metabolismo; Leucina/metabolismo; Masculino; Pessoa de Meia-Idade; Curva ROC; Espectrometria de Massas por Ionização por Electrospray; Valina/metabolismo

Palavras-chave

biomarkers; breath tests; collagen; idiopathic pulmonary fibrosis; metabolomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes Respiratórios / Fibrose Pulmonar Idiopática / Aminoácidos Tipo de estudo: Observational_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respirology Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suíça

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