Multi-omics analysis unravels a segregated metabolic flux network that tunes co-utilization of sugar and aromatic carbons in <i>Pseudomonas putida</i>.

Kukurugya, Matthew A; Mendonca, Caroll M; Solhtalab, Mina; Wilkes, Rebecca A; Thannhauser, Theodore W; Aristilde, Ludmilla

Multi-omics analysis unravels a segregated metabolic flux network that tunes co-utilization of sugar and aromatic carbons in Pseudomonas putida.

Kukurugya, Matthew A; Mendonca, Caroll M; Solhtalab, Mina; Wilkes, Rebecca A; Thannhauser, Theodore W; Aristilde, Ludmilla.

Afiliação

Kukurugya MA; Department of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, United States.
Mendonca CM; Department of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, United States.
Solhtalab M; Department of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, United States.
Wilkes RA; Department of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, United States.
Thannhauser TW; Department of Agriculture-Agricultural Research Service, Ithaca, New York 14853.
Aristilde L; Department of Biological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, United States. Electronic address: ludmilla@cornell.edu.

J Biol Chem ; 294(21): 8464-8479, 2019 05 24.

Article em En | MEDLINE | ID: mdl-30936206

Assuntos

Ácido Benzoico/metabolismo; Ciclo do Ácido Cítrico/fisiologia; Glucose/metabolismo; Glicólise/fisiologia; Metaboloma/fisiologia; Pseudomonas/metabolismo; Proteínas de Bactérias/metabolismo; Metabolômica

Palavras-chave

Pseudomonas; bacterial metabolism; benzoate; fluxomics; glucose; metabolic flux; metabolic regulation; metabolomics; mixed carbon metabolism; proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas / Ciclo do Ácido Cítrico / Ácido Benzoico / Metaboloma / Glucose / Glicólise Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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